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In modern cars with in tank fuel filters I think the biggest risk you have is damaging the fuel pump by running hot/overheating. If you live in a cold climate (which LA really isn't) condensation in the fuel tank can be a problem when running with a low fuel level and coming from warm garage to cold outside. This causes the fuel system the breath in some outside air (water vapour) when fuel vapors collapse/condense. I am not sure in this case what the M5's vacuum tolerance is before it "breathes in".
If I store my car (in Northern Canada M5 gets the winter off) I would always make sure she is full of fuel and ready to go in spring. For a daily driver I am sure it doesn't matter as you can enjoy your M5 year round!
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